The best way would be to clean install. To do a clean install, either boot
the Windows 2000 CD-Rom or setup disks. The set of four install disks can be
created from your Win2k CD-rom; change to the \bootdisk directory on the
cd-rom and execute makeboot.exe (from dos) or makebt32.exe (from 32 bit) and
follow the prompts.
When you get to the point, delete the existing NTFS and or other partitions
found. After you delete the partition(s) abort the install, then again
restart the pc booting the CD-Rom or setup disks to avoid unexpected drive
letter assignments with your new install.
During Windows 2000 setup, at some point, will want to confirm the previous
operating system for the upgrade; at that point you'll simply insert the
qualified product install CD for it to verify. Then the install will
proceed.
Check the pc, mb or hardware manufacturer's web site for the latest bios and
or Windows 2000 drivers for your devices.