You can test whether the regression explains more than a simple mean by doing
a t-test on the estimated slope. Divide the estimated slope by its standard
error to get t and check that the value of TDIST(ABS(t),df) is appropriately
small (often p<0.05). Lack of significance does not mean that the
relationship is not real, instead, it might indicate that you simply do not
have enough data, given the data variability.
For example, with the data set given in Help for the SLOPE function,
=TDIST(ABS(INDEX(LINEST(ydata,xdata,,TRUE),1,1)/INDEX(LINEST(ydata,xdata,,TRUE),2,1)),INDEX(LINEST(ydata,xdata,,TRUE),4,2),2)
returns 0.60 indicating that the linear regression slope is not
statistically significant. A plot of the data suggests a curved relationship
with multiple y values for a single x value (possibly due to additional
predicter variables that have not been supplied) rather than a straight line.
Beware of using R-squared alone for comparing alternate models, as that may
lead to over-fitting your data
http://en.wikipedia.org/wiki/R-squared#Adjusted_R2
Jerry