Seriously, if you want to get help you have to provide more information.
Start with:
1. What you've already done.
2. The make/model/connection method of the printer.
3. The answer to the First Question of Troubleshooting: what changed between
the time things worked and the time they didn't?
In general, things to clear the printer queue (if this is what you really
mean):
1. Reboot the computer.
2. Turn off and unplug the printer.
3. Stop and start the spooler service.