Try PopNot from www.hdsoft.com/popnot
You can download a 15 day evaluation, then it's around
$15 to purchase if you like it. I've been using PopNot
for about 2 years, and recently some pop-ups do get
through, but not nearly as many as get 'killed' (maybe
1/10th). I hope they are working on an upgrade, but I'm
not so dissatisfied as to pay $30 for a retail pop-up
killer. I feel I'm getting my $15 worth!