You should *never* run without a page file, no matter how much memory
you have. If you did so, you wouldn't be able to use all the RAM you
have. That's because Windows pre-allocates page file space, in
anticipation of possibly needing to use it. Although that
pre-allocation speeds up page file use if it's needed, in most cases
if you have enough RAM, that pre-allocated space is never needed and
never actually gets used.
But if there is no page file, that pre-allocation has to get made in
real memory (RAM) instead. That means that the space for that
pre-allocation (and it can be substantial) is tied up and not
available for any other use.