The software part is easy, since you can send a character(s) from the serial
port with a command like:
Open "Com1:4800,n,8,1" for output as #1 'open the port Com1
Print #1,"AAAA" 'arbitrary string of characters
Close #1 'close the port
This will set the port DTR and RTS lines to the opposite state, and put a
string of pulses on the TX line.
What you do with these in hardware to physically open the till is up to you.
At the very least you will need a couple of transistors, a power supply and
a solenoid in the till mechanism to release the latch.
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Regards,
Adrian Jansen
J & K MicroSystems
Microcomputer solutions for industrial control