Rick,
Lot's of programs. Photoshop, Firefox, Lightroom, Windows Media Player to
name a few of the regulars. With Photoshop if I just wait it out the program
finishes the process and the message goes away. Vista just seems to jump the
gun a lot.
Either too much is loading at boot, or you have some spy/adware loaded.
First place the system in diagnostic mode by running msconfig from the
search line. It's on the general tab. After rebooting, see if the problems
still occur while running a couple of programs. If not, then the problem
lies in all the software that was disabled, the startup tab of that utility
will have the list. If it's still happening, run full system scans with your
preferred antivirus and antispyware applications.