In the past Dell has used proprietary pinouts on the MB connector on
the PSU, forcing the use of a Dell PSU if the original fails, or a
Dell MB if the original of that fails. If a standard PSU will fit, I
don't see any reason not to upgrade the PSU at the same time. Dell
has also used proprietary locations for attachment holes in MBs, so
that may be an issue also...
Normally, unless the new motherboard is virtually identical to the
old one (same chipset, IDE controllers, etc), you'll most likely need
to perform a repair (a.k.a. in-place upgrade) installation, at the
very least (and don't forget to reinstall any service packs and
subsequent hot fixes):
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