It means "times 10 raised to the power of". 1E2 is 100, 5E3 is 5,000
etc.
Press F1, and in Help Topics type "scientific format". You should see a
help section called "Formats for currency, percentages, and exponential
notation". If there are too many hits, change Options.. from "at least
one of the words you typed" to "All the words you typed".