You're not giving much to go on so here is my guess.
In Page Setup you've set Scaling to Fit to: x_Pages by x_Pages. And your
printout is too small and not close to the margins.
If that's the case there are most likely "Space" characters in one or more
cells beyond the area you wish to print. A space is a printable character so
unless a specific print area is Set (Select the print range then File>Print
Area>Set Print Area), Excel will extend the print area to the last used cell
on the sheet.
Removing any spaces in or deleting the rows and columns beyond the area you
want to print or setting a print area should resolve the issue.
Best wishes,
Dave