Access is a power saw. If you want to make cabinetry, or frame a house, you
need to know how to run it.
This is very similar to Word or Excel. But in both those instances, folks
are more likely to have real-world experience with something similar (i.e.,
a written document, a ledger-based spreadsheet) than they are with a
database.
When you say "set up", what do you want Access to be doing?