Possibly. What are your preventing? (what process would occur that you don't
want to happen if there are blanks)
One simple way is:
=COUNTBLANK(A2,B2,C3:C6)=0
Where you refer to all the cells you don't want blank. Formula returns a
boolean, which can be used in various ways to stop/halt/notify people.
You might also look into using the formula in Data-Validation.