You can't format a cell to round up, but you can use an event macro:
Put this in your worksheet code module (right-click the worksheet tab
and choose View Code):
Private Sub Worksheet_Change(ByVal Target As Excel.Range)
Dim rTargets As Range
Dim rCell As Range
Set rTargets = Intersect(Target, Range("A1:A10,B2,J10"))
If Not rTargets Is Nothing Then
For Each rCell In rTargets
With rCell
If IsNumeric(.Value) Then
Application.EnableEvents = False
.Value = Application.RoundUp(.Value, 0)
Application.EnableEvents = True
End If
End With
Next rCell
End If
End Sub
Change the Range("A1,B2,J10") to suit.