Sounds like something is looking for a file on the secondary ide controller.
Most manufacturers use this for CD/DVD drives. Did you install something
(like a new piece of hardware or new program) prior to this starting to
happen?
I think it started to happen when I installed broadband and noticed quiet a
lot of different things happening, so I have installed zonealarms pro as my
firewall, macfee as my virus software. Found lots of spyware which were
causing some of the problems I was experiencing and this (as far as I know)
is the last problem that remains.
I find several references to this error and ZA Pro, try uninstalling it to
see what happens. Make sure the native firewall is enabled when you do to
stay protected.