I'm in the midst of evaluating enterprise versions for my company as well.
It's very disappointing that there does not appear to be a good one out
there right now. Pest Patrol and Spysweeper failed. Pest Patrol has issues
with real time protection and false positives. It is fairly strong in
controlling false positives with exceptions, but it fails badly on real time
protection. Spysweeper was a little stronger in real time protection but
they have no way to exclude drives and/or folders from a scan. You can only
exclude file types. Both require network administrators to support the
operation of the software. I don't know about other enterprises, but with
over 10,000 users and 1000 servers we don't want to tie up a network admin
cleaning spyware. These things need to have the ability to use network
admins for configuration and control but allow a web based console to be
accessed with lesser permissions to take care of the workstations. Next up
for us is CounterSpy by Sunbelt Software, Intermute and the LanDesk Suite.
I don't have high expectations for any of them in a network environment.
One of our rules is that we can not test BETA at all, so Microsoft is not
even under consideration since they do not presently have an enterprise
version and when they do it will certainly be BETA for awhile. Maybe next
year...
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Spider
http://web.tampabay.rr.com/spider1
http://spider1.blogspot.com/