If these are "Messenger Service" popups, here's some info: http://www.lavahelp.com/articles/v6/03/05/0302.html
For other types of popups, Popup Manager (free) works
well. You can get it here: http://www.endpopups.com/
Download and run Adaware (free version) from http://www.lavasoftusa.com/
It detects and safely removes dataminers, tracking
cookies, dialers, BHO's and other objects from your
computer. Use "webupdate" before you scan to make sure
you have the latest ref file (open Adaware and click on
the globe or "Check for Updates Now"). The ref files are
updated frequently - sometimes several times a week. .
Run a "full scan" http://www.lavahelp.com/howto/fullscan/index.html
If you have any questions, their forums are here http://www.lavasoftsupport.com/