I cannot state positively that Vista would
support the SATA-DVD, but it should. The
primary factor affecting this in Win XP was the
motherboard chips. Some would enable
recognition of the SADA Optical drive for
boot-up and installation of the system and
others would not. I think that if you are able
to configure your BIOS to see the SATA channel
as SATA and not SATA-RAID it should work. My
Asus board does not have the option for this,
but my MSI board does.