You can put the desired titles in their respective columns in row 1, then
disable row and column headers by unchecking the option under Tools >
Options > View.
But the last step is usually undesirable because you will still want to use
cell reference indicated by row and column, unless you have a lot of named
ranges.
The more common requirement is simply to not show row and column headers
when you __print__. That can be accomplished by disabling row and column
headers under Page Setup > Sheet.