To tell you the truth, I've had some very good luck with Vista and replacing
motherboards. I shouldn't have done it that way, but I did... Kinda went
against my own advice and just replaced the board, CPU, RAM, video card (had
to reactivate, but it ran fine). Went from an Abit AMD board with Athlon 64
4400+ and an AGP ATI video card to a Gigabyte P35 Intel board with a Core 2
Duo 6800 and DDR2 RAM and a PCI-e ATI video card. Rebooted and it came up to
the desktop, loaded drivers, had to reactivate and I was good to go.
I
wasn't expecting it, but I was eager to get back up and going. Soon after, I
did reinstall as it was a good idea to do...
You might have to do a startup install. I'm not sure if doing an upgrade on
that would work, but it might.