If you have a good handle on Excel and Word, then you have the basic skills
you need to know how to navigate around any MS application. That along with
knowing how to use the help files and online sources of MS for FrontPage...
I would say you have what you need to get started and produce a decent
website.
FP is designed to be a canned product with all of the basic tools you need
to get the job done. I can't say that you should take a course. That depends
on the school/instructor offering the course and your learning style.
Take a look at this MS website with training modules and see for yourself if
you can do this without a course.
http://office.microsoft.com/en-us/training/CR061832701033.aspx
I think you'll find you don't need one, however... taking a basic course in
HTML might be advantageous down the road. As far as design, there are quite
a few good training modules on MS that helps a person who may be design
challenged. I would look at design from two different perspectives, design
from a "visual" point of view, e.g., font selection, colors, etc. and design
from the "mechanics" point of view, using the various tools and web
structure.
Hope this helps,
Steve Banks